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Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

CD13 activation assembles phosphoinositide (PI) signaling complexes to regulate the actin cytoskeleton. [PDF]

open access: yesSci Rep
Meredith E   +8 more
europepmc   +1 more source
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NLTE line formation

Physica Scripta, 2008
I review some of the present achievements and future challenges of non-local thermodynamicequilibrium (NLTE) line-formation calculations for solar-type stars.
openaire   +1 more source

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