Results 61 to 70 of about 2,085,603 (265)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The star formation history of early-type galaxies in the fornax cluster [PDF]

, 1998
We have measured central line strengths and line-strength gradients for a complete sample of early-type galaxies in the Fornax cluster, comprising 11 elliptical and 11 lenticular galaxies, more luminous than M(_B) = -17.
Kuntschner, Harald, Kuntschner, H.
core  

Robot line formation

, 2009
Tese de mestrado integrado. Engenharia Electrotécnica e de Computadores. Faculdade de Engenharia. Universidade do Porto, Faculty of the Graduate School. University of Maryland. 2009
openaire   +2 more sources

3D NLTE spectral line formation of lithium in late-type stars. [PDF]

Mon Not R Astron Soc, 2021
Wang EX, Nordlander T, Asplund M, Amarsi AM, Lind K, Zhou Y.   +5 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Line profiles of cores within clusters. II. Signatures of dynamical collapse during high-mass star formation

, 2013
R.J.S, R.S, and R.S.K. acknowledge support from the DFG via the SPP 1573 Physics of the ISM (grants SM321/1-1, KL 1358/14-1, and SCHL 1964/1-1).Observations of atomic or molecular lines can provide important information about the physical state of star ...
Ian A. Bonnell, Rahul Shetty, Ralf S. Klessen, Bonnell, I.A., Beuther, H, Rowan J. Smith, Henrik Beuther, Shetty, R., Klessen, R S, Smith, R J, Klessen, R.S., Bonnell, I A, Beuther, H., Shetty, R, Smith, R.J.   +14 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The formation of molecular hydrogen in the interstellar medium

, 2010
H2 is the most abundant molecule in the interstellar medium and forms on the surface of interstellar dust grains. Laboratory studies have been conducted of HD formation on a dust grain analogue, which is a highly-oriented pyrolytic graphite surface ...
Islam, F.
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source