Results 31 to 40 of about 959,893 (266)
Anomalous Fraunhofer Line Profiles [PDF]
Nature, 1962 DURING the spring of 1961 we made observations of the H line of Ca(II) in the spectrum of moonlight, with the view of detecting any luminescent radiation which might have been present. The observations were made with the 50-in. reflector of the University of Padua's Observatory at Asiago.
J. F. GRAINGER, J. RING
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Profile line accuracy in cephalometric radiographs
American Journal of Orthodontics and Dentofacial OrthopedicsIntroduction This study investigates the accuracy of facial soft-tissue profile lines in lateral cephalometric radiographs by comparing them to true profile lines derived from 3-dimensional photographs.Methods This prospective methodological study was performed on preexisting records of 100 orthodontic patients.
Marie-Laure Arn +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Line Profiles of Faculae and Pores [PDF]
Highlights of Astronomy, 1977 Historically, attempts to model the temperature structure of faculae have generally suffered from a rather basic contradiction. Models which were based on center to limb measurements of the continuum contrast of faculae disagree with models that are based on measurements of line profiles in faculae.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Data-driven analysis of neutron diffraction line profiles: application to plastically deformed Ta. [PDF]
Sci Rep, 2022 Tallman AE +7 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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