Results 221 to 230 of about 4,813,932 (329)

LINE-1 transposition into murine Thyroglobulin results in congenital thyroid dysplasia. [PDF]

PLoS One
Bailey WJ, Smits BMG, Erdos Z, Gaspar JM, Lane P, Kuruvilla S, Rosahl TW, Thudium D, Wang J, Glaab WE, MacGowan M, Multari H, Cumo C, Navis A, Forest T.   +14 more
europepmc   +1 more source

Generation and validation of a Leber Congenital Amaurosis, Type 12 patient-specific iPSC line (LVPEIi006-B) with a splice-site mutation in RD3 and an isogenic mutation-corrected iPSC line (LVPEIi006-B-1)

Sudipta Mahato, Savitri Maddileti, Trupti Agrawal, Sundaram Acharya, Chitra Kannabiran, Subhadra Jalali, Debojyoti Chakraborty, Indumathi Mariappan   +7 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Development of Automated Production Line Processes for Solar Brightfield Modules: Final Report, 1 June 2003-30 November 2007

, 2008
M. J. Nowlan
openalex   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The oncogenic microRNA miR-222 promotes human LINE-1 retrotransposition. [PDF]

RNA Biol
Friehmann T, Abu Mohsen Y, Schlesinger Y, Ghantous L, Gamaev L, Landau Zenilman C, Harazi A, Galun E, Goldenberg DS.   +8 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

LINE-1, the NORth star of nucleolar organization. [PDF]

Genes Dev
Matsuo M, Cristofari G.
europepmc   +1 more source

Impact of Dolutegravir plus Lamivudine as First-Line Antiretroviral Treatment on HIV-1 Reservoir and Inflammatory Markers in Peripheral Blood

Lucía Bailón, María C. Puertas, Maria C. García-Guerrero, Igor Moraes-Cardoso, Ester Aparicio, Yovaninna Alarcón‐Soto, Àngel Rivero, Elias P. Rosen, Jacob D. Estes, Julià Blanco, Àlex Olvera, Beatriz Mothe, Javier Martínez‐Picado, José Moltó   +13 more
openalex   +1 more source

Study of antitumor activity of natural type IFN-.GAMMA.(OH-6000) for nude mouse transplantability malignant melanoma ( SK-14 line ) and renal cancer ( RCC-1 line ).

, 1990
Toshio OGATA, Kazuyuki ISHIHARA, Naoya Yamazaki, Hideya SASAKI, Tsutomu Koide, Teruo KOMATSU   +5 more
openalex   +2 more sources