Results 221 to 230 of about 17,428,143 (356)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Recurrent hematological toxicity after second-line treatment in patients with glioblastoma: indication of a potential predisposition. [PDF]

Oncologist
van Hout L, van den Elzen FEL, de Jong Z, Grun N, Broen MPG, Bartelink I, Bruynzeel AME, Lagerwaard FJ, Buter J, Vandertop WP, Westerman BA, Lissenberg-Witte BI, Kouwenhoven MCM.   +12 more
europepmc   +1 more source

Activity and safety of first-line treatments for metastatic renal cell carcinoma in older patients, Gustave Roussy experience

Maxime Frélaut, Augusta d'Huy, C. Matthias Wilk, C. Vauchier, Natacha Naoun, Zachariah Thomas, Capucine Baldini, Ronan Flippot, Laurence Albigès   +8 more
openalex   +1 more source

Asymmetric emission of the [OIII]λ5007 profile in narrow-line Seyfert 1 galaxies [PDF]

, 2018
E. O. Schmidt, G. A. Oio, D. Ferreiro, L. Vega, W. Weidmann   +4 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Key structural parameters of the two-stage injection jet on-line mixer.

Ping Jiang (243020), Siliang Xiang (21587153), Wenwu Hu (19142074), Yahui Luo (21587156), Wen Li (143214), Xiang Dong (550906), Yixin Shi (5404316)   +6 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A meta-analysis of broiler chicken meat quality: Comparative evidence of halal slaughter and electrical stunning. [PDF]

Poult Sci
Okon UM, Hayat MN, Nuamah E, Radzi MAM, Othman AH, Sazili AQ.   +5 more
europepmc   +1 more source

Youth olympic games: challenges and considerations in organising the largest multisport competition for young athletes [PDF]

, 2010
Balduck, Anne-Line, Lucidarme, Steffie, Maes, Marc, Magherman, Leen   +3 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source