Results 221 to 230 of about 9,613,096 (307)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Survival outcomes with Lutetium-177-PSMA-617 in metastatic castration-resistant prostate cancer patient according to baseline tumor characteristics. [PDF]

World J Urol
Wenzel M, Le QC, Siech C, Hoeh B, Klimek K, Happel C, Saad F, Preisser F, Tilki D, Graefen M, Steuber T, Maurer T, Kriegmair MC, Karakiewicz PI, Chun FKH, Groener D, Mandel P.   +16 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Impact of thrombectomy techniques on outcome in medium or distal vessel occlusion: subanalysis of the DISTAL Trial. [PDF]

J Neurointerv Surg
Schulze-Zachau V, Rommers N, Dobrocky T, Hajdu SD, Fiehler J, Fragata I, Gralla J, Machi P, Kirschke JS, van Es ACGM, Kaesmacher J, Buhk JH, Saver JL, Martínez-Galdámez M, Piechowiak EII, Kaiser DPO, Tancredi I, Van Den Bergh F, Hellstern V, Khanafer A, Volders D, Strbian D, Ribo M, Karwacki GM, Aebischer V, Brehm A, Fischer U, Psychogios MN, Collaborators D.   +28 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Correction: Enhanced performance in transparent conducting materials at the interface of a wide band gap semiconductor and a correlated metal.

Mater Horiz
Stoner JL, Batuk M, Manning TD, Dyer MS, Hadermann J, Rosseinsky MJ, Alaria J.   +6 more
europepmc   +1 more source

Profile Study on Different Patterns in PMMA Bilayer Resist Configurations Under 20 keV Electron Beam Exposure. [PDF]

Nanomaterials (Basel)
Kostic I, Manoilov E, Bencurova A, Koleva E, Andok R, Vutova K.   +5 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Correction: Allosteric coupling in ligand-gated ion channels. [PDF]

J Gen Physiol
Colquhoun D, Lape R.
europepmc   +1 more source