Results 121 to 130 of about 6,450,706 (320)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Perturbative bootstrap of the Wilson-line defect CFT: Bulk-defect-defect correlators

Journal of High Energy Physics
Abstract We study the correlators of bulk and defect half-BPS operators in $$ \mathcal{N} $$ N = 4 Super Yang-Mills theory with a Maldacena-Wilson line defect, focusing on the case involving one bulk and two defect local ...
Daniele Artico, Julien Barrat, Yingxuan Xu   +2 more
openaire   +5 more sources

Study of the Cu(111) Surface by Scanning Tunneling Microscopy: The Morphology Evolution, Reconstructions, Superstructures and Line Defects. [PDF]

Nanomaterials (Basel), 2022
Qu Z, Wang X, Shen X, Zhou H.
europepmc   +1 more source

Columnar defects and vortex fluctuations in layered superconductors

, 1995
We investigate fluctuations of Josephson-coupled pancake vortices in layered superconductors in the presence of columnar defects. We study the thermodynamics of a single pancake stack pinned by columnar defects and obtain the temperature dependence of ...
A. Buzdin, A. E. Koshelev, C.J. van der Beek, D.R. Nelson, D.R. Nelson, G.S. Mkrtchyan, H. Pastoriza, J. Blatter, L. Civale, L. Klein, L. Krusin-Elbaum, L.I. Glazman, L.L. Daemen, M. Konczykowski, M. Konczykowski, P. Le Doussal, R.P. Feynman, S. Ryu, V. M. Vinokur, W. Gerhäuser, W.R. White, W.R. White   +21 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Fast Blob and Air Line Defects Detection for High Speed Glass Tube Production Lines. [PDF]

J Imaging, 2021
De Vitis GA, Di Tecco A, Foglia P, Prete CA.   +3 more
europepmc   +1 more source

Wide-field reflective scanning optical systems [PDF]

, 1973
Catoptric optical scanning system provides relatively fast line-scan rate for two-dimensional coverage. Rapid scan rates require low focal ratios between components and smallest possible masses.
Abel, I. R.
core   +1 more source

Commuting Line Defects At $$q^N$$ = 1

Communications in Mathematical Physics
35 pages, 7 figures, 1 Mathematica notebook attached as ancillary ...
Davide Gaiotto, Gregory W. Moore, Andrew Neitzke, Fei Yan   +3 more
openaire   +2 more sources