Results 101 to 110 of about 10,691,328 (287)

Scattering off of twistorial line defects

open access: yesJournal of High Energy Physics
A bstract The recently devised chiral algebra bootstrap computes the form factors of a special class of “twistorial” 4d QFTs as correlation functions of the theory’s 2d celestial chiral algebra. Examples of twistorial theories include self-dual Yang-Mills
Niklas Garner, Natalie M. Paquette
openaire   +3 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Planar RG flows on line defects

open access: yesJournal of High Energy Physics
A bstract We study a class of renormalization group flows on line defects that can be described by a generalized free field with ordered planar contractions on the line.
Ivri Nagar, Amit Sever, De-liang Zhong
openaire   +3 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Perturbative bootstrap of the Wilson-line defect CFT: Bulk-defect-defect correlators

open access: yesJournal of High Energy Physics
A bstract We study the correlators of bulk and defect half-BPS operators in $$ \mathcal{N} $$ N
Daniele Artico   +2 more
openaire   +5 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Line Defects in One-Dimensional Hexagonal Quasicrystals [PDF]

open access: yes
Using the eight-dimensional framework of the integral formalism of one-dimensional quasicrystals, the analytical expressions for the displacement fields and stress functions of line defects, which are dislocations and line forces, in one-dimensional ...
Markus Lazar, Lazar, Markus
core   +2 more sources

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

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