Results 191 to 200 of about 8,892,596 (302)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Feasibility and Preliminary Effects of AI-Generated Personalized Sleep Feedback in High School Female Soccer Players: Pilot Randomized Controlled Trial. [PDF]

JMIR Form Res
Kedoin H, Itoh Y, Nirengi T, Sato Y, Sugisawa S, Nishio Y, Akitsu R.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Stable tetraploid olive (<i>Olea europaea</i> L.) plants derived from embryogenic cultures show altered growth and improved water retention. [PDF]

Front Plant Sci
Ribalta L, Palencia F, Narváez I, Martín AC, Mercado JÁ, Pliego-Alfaro F, Palomo-Ríos E.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Acute and prolonged effects of anti-malarial drugs on mitochondrial respiration in atrial cardiomyocytes for cardiac safety evaluation. [PDF]

PLoS One
Safakli RN, Lee B, Chadda KR, Sathivelu S, Smyrnias I, Huang CLH, Tarning J, Terracciano C, Tse G, Edling CE, Jeevaratnam K.   +10 more
europepmc   +1 more source

Comparison between Power Efficiencies of Mixed-Line Rate over Single-Line Rate in Spectral Efficient WDM Networks with Signal Quality Guarantee

Mixed-Line Rate (MLR) in a cost-efficient manner scope with the heterogeneous nature of constantly increasing traffic demands in core networks. In the same time, telecom operators have to decide how to introduce into the system new 10G, 40G, and/or 100G ...
Bobrovs, Vjačeslavs, Ivanovs, Ģirts, Udaļcovs, Aleksejs   +2 more
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Technical efficiency in hip arthroscopy plateaus after approximately 240 cases while complication rates continue to decline: A 15-year single-surgeon series of 1490 consecutive procedures. [PDF]

J Exp Orthop
Mei A, Clausetti L, Metrop M, Girardot G, Bonin N.   +4 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source