Results 151 to 160 of about 9,967 (308)

Analysis of Temperature Field of Involute Spur Gear based on Friction Influence

Jixie chuandong, 2015
Taking apair of involute spur gear as the object of study,by using the formula of the friction coefficient obtained from the prophase study and the multi-bodied dynamics software ADAMS,it is possible to calculate the heat flow of friction at any point on
Li Baoliang, Bi Lin, Tao Xuejuan
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

APLIKASI LOGIKA FUZZY PADA ROBOT LINE FOLLOWER BERBASIS ATMEGA 8535 MENGGUNAKAN BAHASA PEMROGRAMAN C

, 2010
Proyek Akhir ini bertujuan untuk dapat membuat hardware robot line follower dan software kendali logika fuzzy sebagai sistem navigasi robot serta mengetahui unjuk kerja aplikasi logika fuzzy pada robot line follower yang dikendalikan dengan sebuah ...
Nugroho, Faisal Nuriskananto
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Basaloid follicular hamartoma following Blaschko’s lines

Anais Brasileiros de Dermatologia, 2022
Gabriela Martins de Queiroz, Tayla Cristina Lopes, Maria Clara Dantas Valle Soares, Carlos Bruno Fernandes Lima   +3 more
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Telekit: a bilateral, teleoperated platform for hands-on learning. [PDF]

Front Robot AI
Bie C, Kuling IA, Legrand J.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Implementasi Infrared Barrier Obstacle Sensor Menggunakan Modul Hw-201 Pada Smart Car Robot Line Follower

This research discusses the implementation of an infrared barrier obstacle sensor using the HW-201 module on a smart car robot line follower. The main aim of this research is to improve the ability of the smart car robot line follower to detect and ...
Toni Rahmat Wahyu, Ranti Imawati, Rejeki, Sri, Haris Priazun, Amin Widodo, Febiyana Firdaus   +5 more
core   +1 more source