Results 171 to 180 of about 9,967 (308)

Mechanisms Underlying the Initiation and Termination of Collective Cell Migration: Perspectives for Understanding Development and Cancer Metastasis. [PDF]

Bioessays
Miao G.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Protocol to quantify glioblastoma cell invasion and nuclear deformations in 3D hydrogels. [PDF]

STAR Protoc
van Bodegraven EJ, Kesenci Y, Olivo-Marin JC, Boquet-Pujadas A, Etienne-Manneville S.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Analyzing gaze and hand movement patterns in leader-follower interactions during a time-continuous cooperative manipulation task. [PDF]

Front Psychol
Cheng M, Zahedi A, Schubotz RI, Wörgötter F, Tamosiunaite M.   +4 more
europepmc   +1 more source

Autonomous Line-Following Robot

International Journal of Advanced Research in Science Communication and Technology
Autonomous monitoring systems are increasingly required in hazardous and restricted industrial environments where human presence may pose safety risks. This paper presents the design and implementation of an autonomous line-following robot capable of performing real-time industrial parameter monitoring and wireless data transmission.
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Sensor based autonomous color line follower robot with obstacle avoidance

, 2013
Proceeding of Business Engineering and Industrial Applications Colloquium 2013 (BEIAC 2013) at Langkawi, Malaysia on 7 April 2013 through 9 April 2013.This paper introduces the multiple source Multiple Destination Robot (MDR-1) having the ability to ...
Kazi Mahmud, Hasan, Abdullah, Al-Nahid, Sabira, Khatun, Prof. Dr., Md Rubel, Basar, Khondker Jahid, Reza   +4 more
core  

How Bodily Interaction Shapes Creativity: Two Experiments on Direction and Type. [PDF]

Behav Sci (Basel)
Su J, Ye H.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source