Results 181 to 190 of about 13,917,092 (356)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Long-read transcriptomic profiling of a glioma cell line following m6A regulator perturbations. [PDF]

Biochem Biophys Rep
Lee H, Batool SM, Escobedo AK, Gashi D, Faber K, Ponnolu P, Barretts NR, Khanna P, Haas KD, Hsia T, Carter BS, Balaj L.   +11 more
europepmc   +1 more source

Basaloid follicular hamartoma following Blaschko’s lines

Anais Brasileiros de Dermatologia, 2022
Gabriela Martins de Queiroz, Tayla Cristina Lopes, Maria Clara Dantas Valle Soares, Carlos Bruno Fernandes Lima   +3 more
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Secretory Profile Analysis of Human Granulosa Cell Line Following Gonadotropin Stimulation. [PDF]

Int J Mol Sci
Mancini F, Teveroni E, Cicchinelli M, Iavarone F, Astorri AL, Maulucci G, Serantoni C, Hatem D, Gallo D, Di Nardo C, Urbani A, Pontecorvi A, Milardi D, Di Nicuolo F.   +13 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Antiviral Effects of Tecovirimat and Cellular Ultrastructural Changes in Human Bronchial Epithelial Cell Line Following Monkeypox Virus Infection. [PDF]

Int J Mol Sci
Falasca L, Mija C, Sberna G, Francalancia M, Meschi S, Mazzotta V, Girardi E, Antinori A, Maggi F, Bordi L.   +9 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Episodes 3 and 4 of Radio Program LIFE LINE

, 1958
Two episodes of the conservative religious radio program \u27LIFE LINE\u27 devoted to the topic of the U.S. Supreme Court and the communist conspiracy. Following the opening commentary on the Supreme Court in Episode 3 is a hymn, a narrative about golf ...
Life Line (Radio program), Poucher, Wayne   +1 more
core  

Intravenous mishap following residual anesthetic drug in intravenous extension line

Saudi Journal of Anaesthesia, 2017
Udismita Baruah, R Karthiga, Rajeshwari Subramaniam   +2 more
doaj   +1 more source