Results 91 to 100 of about 4,935,854 (284)

BOREL LINE GRAPHS

The Journal of Symbolic Logic
Abstract We characterize Borel line graphs in terms of 10 forbidden induced subgraphs, namely the nine finite graphs from the classical result of Beineke together with a 10th infinite graph associated with the equivalence relation $\mathbb {E}_0$ on the Cantor space.
JAMES ANDERSON, ANTON BERNSHTEYN
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Collapsible graphs and reductions of line graphs

Discrete Mathematics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chen, Zhi-Hong, Lam, Peter C.B., Shiu, Wai-Chee   +2 more
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Padmakar-Ivan index of some types of perfect graphs [PDF]

Discrete Mathematics Letters, 2022
Manju Sankaramalil Chithrabhanu, Kanagasabapathi Somasundaram   +1 more
doaj   +1 more source

Some properties of Cayley signed graphs on finite Abelian groups

Electronic Journal of Graph Theory and Applications
This paper establishes explicit combinatorial characterizations for fundamental structural properties of Cayley signed graphs defined on finite Abelian groups.
Mohammad A. Iranmanesh, Nasrin Moghaddami   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

On •-Line Signed Graphs L•(S)

Discussiones Mathematicae Graph Theory, 2015
A signed graph (or sigraph for short) is an ordered pair S = (Su,σ), where Su is a graph, G = (V,E), called the underlying graph of S and σ : E → {+,−} is a function from the edge set E of Su into the set {+,−}.
Sinha Deepa, Dhama Ayushi
doaj   +1 more source

GENERAL APPROACH TO LINE GRAPHS OF GRAPHS

Demonstratio Mathematica, 1985
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marczyk, Antoni, Skupień, Zdzisław
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source