Results 71 to 80 of about 1,370,090 (279)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Edge-Transitivity of Cayley Graphs Generated by Transpositions

open access: yesDiscussiones Mathematicae Graph Theory, 2016
Let S be a set of transpositions generating the symmetric group Sn (n ≥ 5). The transposition graph of S is defined to be the graph with vertex set {1, . . . , n}, and with vertices i and j being adjacent in T(S) whenever (i, j) ∈ S. In the present note,
Ganesan Ashwin
doaj   +1 more source

Oriented gain graphs, line graphs and eigenvalues [PDF]

open access: yesLinear Algebra and its Applications, 2016
A theory of orientation on gain graphs (voltage graphs) is developed to generalize the notion of orientation on graphs and signed graphs. Using this orientation scheme, the line graph of a gain graph is studied. For a particular family of gain graphs with complex units, matrix properties are established.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On an edge partition and root graphs of some classes of line graphs

open access: yesElectronic Journal of Graph Theory and Applications, 2017
The Gallai and the anti-Gallai graphs of a graph $G$ are complementary pairs of spanning subgraphs of the line graph of $G$. In this paper we find some structural relations between these graph classes by finding a partition of the edge set of the line ...
K Pravas, A. Vijayakumar
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

General sum-connectivity index, general product-connectivity index, general Zagreb index and coindices of line graph of subdivision graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2017
The general sum-connectivity index, general product-connectivity index, general Zagreb index and coindices of line graphs of subdivision graphs of tadpole graphs, wheels and ladders have been reported in the literature.
Harishchandra S. Ramane   +2 more
doaj   +1 more source

On-line list colouring of random graphs [PDF]

open access: yes, 2015
In this paper, the on-line list colouring of binomial random graphs G(n,p) is studied. We show that the on-line choice number of G(n,p) is asymptotically almost surely asymptotic to the chromatic number of G(n,p), provided that the average degree d=p(n-1)
Alan Frieze   +5 more
core   +3 more sources

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