Results 61 to 70 of about 6,649,681 (287)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

L-Index-Based Technique for Voltage Collapse Prediction and Voltage Stability Enhancement in Electrical Power Systems

ABUAD Journal of Engineering Research and Development
Recent years have witnessed a notable increase in the occurrence of blackouts, especially in developing nations, attributed to the continuously growing demand on modern power networks.
Akintunde Samson Alayande, Amirah Opeyemi Hassan, Flourish Olobaniyi, Samuel Olufemi Osokoya, Azeez Ishola Adebeshin, Ayoade Benson Ogundare   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Power System Voltage Stability Analysis [PDF]

, 2011
Power system is facing new challenges as the present system is subjected to severely stressed conditions. Voltage instability is a quite frequent phenomenon under such a situation rendering degradation of power system performance.
Reddy, C M
core  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A Research Project to Investigate the Impact of Electricity System Requirements On the Design and Optimal Application of the Powerformer (TM) [PDF]

, 2001
This paper describes the aims and the methodology of a major collaborative research project between the University of Queensland and Australian and Swedish industry partners, including ABB Corporate Research (Sweden), Alstom Power (Sweden and Australia),
Berggren, B., Darveniza, M., Leijon, M. A., Saha, Tapan K., Wright, P. O.   +4 more
core  

Heuristic Approach for Distribution Systems Feeder Reconfiguration to Line Maximum Loadability

International Journal on Electrical Engineering and Informatics, 2012
This paper presents a heuristic approach for optimal feeder reconfiguration of radial distribution systems (RDS). Optimal feeder reconfiguration involves the selection of the best set of branches to be opened by considering the all tie switches, such that the resulting RDS has the desired performance. Amongst the several performance criteria considered
K Nagaraju, S Sivanagaraju, T Ramana, V Ganesh   +3 more
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Determination of static voltage stability-margin of the power system prior to voltage collapse. [PDF]

, 2011
yesVoltage instability problems in power system are an important issue that should be taken into consideration during the planning and operation stages of modern power system networks.
Jalboub, Mohamed K., Ihbal, Abdel-Baset M.I., Rajamani, Haile S., Abd-Alhameed, Raed A.   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source