Results 71 to 80 of about 6,649,681 (287)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
‘Turnaround’ of Indian Railways: Increasing the Axle Loading [PDF]
Axle loading had contributed significantly to the ‘turnaround’ of the Indian Railways (IR) in the two years 2004-06. As the Minister of Railways (MR) stated, “A one ton extra loading per wagon implied additional revenue of Rs 500 crore per annum for IR.”
Raghuram, G., Shukla Niraja
core
Reliability evaluation of power system considering voltage stability and continuation power flow [PDF]
, 2007 This article describes the methodology for evaluation of the reliability of an composite electrical power system considering voltage stability and continuation power flow, which takes into account the peak load and steady state stability limit.
Bansal, R. C. +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Application of the generalized reduced gradient method to conceptual aircraft design [PDF]
The complete aircraft design process can be broken into three phases of increasing depth: conceptual design, preliminary design, and detail design. Conceptual design consists primarily of developing general arrangements and selecting the configuration ...
Gabriele, G. A.
core +1 more source
ID5.17: New LearnWeb tool v.0.3 evaluation outcomes [PDF]
, 2009 Mazzetti, A., & Perez, M. (2009). ID5.17: New LearnWeb tool v.0.3 evaluation outcomes: TENCompetence.This document describes the evaluation of the new version of LearnWeb2.0, called: LearnWeb v.0.3 and KRService v.0.3.
Mazzetti, Alessandro, Perez, Mar
core
Distributed Monitoring of Voltage Collapse Sensitivity Indices
, 2016 The assessment of voltage stability margins is a promising direction for wide-area monitoring systems. Accurate monitoring architectures for long-term voltage instability are typically centralized and lack scalability, while completely decentralized ...
Bullo, Francesco, Simpson-Porco, John W.
core +1 more source
A Novel Method To Evaluate Line Loadability For Distribution Systems With Realistic Loads
, 2011 {"references": ["C. W. Taylor, Power System Voltage Stability (McGraw-Hill, Inc.,\nNewYork, America, 1994).", "P. W. Sauer, M. A. Pai, Power system steady-state stability and the loadflow\nJacobian, IEEE Transactions on Power Systems, vol. 5 n. 4,\nNovember 1990, pp. 1374 - 1383.", "N. Yorino, H. Sasaki, Y. Masuda, Y. Tamura, M. Kitagawa and A.\nOshimo,
K. Nagaraju +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source