Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
3D mapping of defects and moiré corrugations via electron ptychography atomic coordinate retrieval. [PDF]
Huang J +5 more
europepmc +1 more source
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Bleb expansion requires transient membrane invaginations that sequester curvature-preferring proteins. [PDF]
Maekawa Y +3 more
europepmc +1 more source
Plastic Deformation of the Pediatric Forearm: Recognition, Radiographic Measurement, and Management. [PDF]
Wetzel C, Rohl M, Manes T, Kadado A.
europepmc +1 more source
Atomistic Simulation of Collapse and Recrystallization in Hollow Gold and Silver Nanoparticles with Ultrathin, Porous Walls. [PDF]
Myasnichenko VS +6 more
europepmc +1 more source
Curvature-emergent supramolecular polymerization of a porphyrin dyad with a scissor-shaped motif. [PDF]
Kawai R +4 more
europepmc +1 more source
Automated segmentation and quantitative analysis of vascular curvature features in unruptured intracranial aneurysms based on time-of-flight magnetic resonance angiography (TOF-MRA). [PDF]
Lu Y +5 more
europepmc +1 more source

