Results 191 to 200 of about 19,833 (300)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Real-Time Dry Matter Prediction in Whole-Plant Corn Forage and Silage Using Portable Near-Infrared Spectroscopy. [PDF]

Animals (Basel)
Pupo MR, Diepersloot EC, Paula EM, Dórea JRR, Ghizzi LG, Ferraretto LF.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

An optimized haploid breeding strategy employing genome-edited anthocyanin markers for visual selection in tomato. [PDF]

Plant Commun
Zhou M, Sun C, Zhou K, Yuan G, Deng L, Pan B, Hu X, Du M, Li C, Li C.   +9 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Effects of learning, exercise, and game curriculum model on the physical fitness of preschool children aged 3-6: a cluster-randomized controlled trial. [PDF]

Sci Rep
Shi Z, Yang X, Long X, Liu Z, Xia Q.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The Big BIT maize experiment: A large multi-location, multi-year, multi-tester, multi-population predictive breeding validation study. [PDF]

Plant Genome
Jines M, Chandler M, Podlich D, Baumgarten A, Wright D, Jacobson A, Zhao H, Gogerty J, Regennitter M, Hung HY, McDowell R, Tang T, Diepenbrock C, Helmi H, Messina C, Ross A, Henke G, Spangler L, Caldwell M, Stirling L, Reyes A, Gho C, Cooper M, Arbuckle J, Smalley M, Milach S, Graham G, Totir LR.   +27 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Reliability of a portable device for measuring lower-limb muscle strength in patients who underwent total knee arthroplasty. [PDF]

J Phys Ther Sci
Kuwahara K, Makino Y, Kato T, Fukuda A, Asada K.   +4 more
europepmc   +1 more source