Results 161 to 170 of about 534,399 (300)

Reducing mapping reference and lineage bias in <i>Mycobacterium tuberculosis</i>. [PDF]

Microb Genom
Torres Ortiz A, Didelot X, Grandjean L.
europepmc   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Development and Laboratory Validation of a Field-Deployable CRISPR-Cas12a eDNA Assay for Phylogeographic Lineage Detection in Arctic Char (Salvelinus alpinus). [PDF]

Mol Ecol Resour
Walsh DJ, Hynes R, Guo W, Surgenor C, Prodöhl PA, Parle-McDermott A.   +5 more
europepmc   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Large-scale genomic phylogeography provides insights into evolutionary history and conservation priorities of the white-bellied pangolin (Phataginus tricuspis). [PDF]

Mol Biol Evol
Gu TT, Zhai TY, Jiang Y, Qi BT, Yang F, Zhang ZX, Yu R, Omotosho O, Morenikeji O, Zhang HR, Hu JY, Yu L.   +11 more
europepmc   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

A Dominant Founder Lineage Has Possible Fitness Costs for the Endangered Mexican Grey Wolf. [PDF]

Mol Ecol
Loera Y, Khakoo M, Krueckeberg E, Nilsson IG, Wu Z, Dwire M, Adams J, Waits L, Oakleaf JK, Campbell ML, Dunnum JL, Cook JA, vonHoldt BM.   +12 more
europepmc   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Pan-Continental Genomic Analysis of Eurasian Perch Uncovers Global Diversity Hotspots and Postglacial Recolonization Patterns. [PDF]

Ecol Evol
Lichman V, Ozerov M, López ME, Noreikiene K, Kahar S, Pukk L, Burimski O, Japoshvili B, Blazhekovikj-Dimovska D, Lajus D, Nikolić D, Ribeiro F, Gebauer T, Kouřil J, Peterka J, Blabolil P, Čech M, Jůza T, Kubečka J, Muška M, Šmejkal M, Vašek M, Kahilainen K, Ložys L, Carlsson J, Corcoran W, Yilmaz Ö, Eklöv P, Takács P, Bánó B, Pallos R, Kazakov S, Pehlivanov L, Lecocq T, Lambert S, Lauridsen T, Berthelsen A, Raposeiro P, Verreycken H, Britton R, Borcheling J, Kutsokon Y, Didenko O, Jurajda P, Miranda R, Gross R, Vasemägi A.   +46 more
europepmc   +1 more source