Results 191 to 200 of about 503,355 (348)

Genetic Determinants of Virulence in Pathogenic Lineage 2 West Nile Virus Strains [PDF]

open access: diamond, 2008
Elizabeth M. Botha   +7 more
openalex   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

High Genetic Diversity of Histoplasma in the Amazon Basin, 2006-2017. [PDF]

open access: yesEmerg Infect Dis
Ly T   +16 more
europepmc   +1 more source

A spatial analysis of genetic structure of human populations in China reveals distinct difference between maternal and paternal lineages [PDF]

open access: bronze, 2008
Fuzhong Xue   +9 more
openalex   +1 more source

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

open access: yesAdvanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang   +14 more
wiley   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

open access: yesAdvanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya   +6 more
wiley   +1 more source

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