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Genetics‐Based Targeting Strategies for Precise Neuromodulation
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He+11 more
wiley +1 more source
Monitoring and characterization of canine and feline astroviruses in domestic dogs and cats in Thailand. [PDF]
Thaw YN+8 more
europepmc +1 more source
Genomic Signatures of the Haarlem Lineage of Mycobacterium tuberculosis : Implications of Strain Genetic Variation in Drug and Vaccine Development [PDF]
Andrés Cubillos-Ruiz+8 more
openalex +1 more source
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Nextclade data set for the ORF5-based lineage classification of PRRSV-1. [PDF]
Zeller M+4 more
europepmc +1 more source
West Nile virus isolates from India: evidence for a distinct genetic lineage
Vijay P. Bondre+4 more
openalex +1 more source
De Novo Reconstruction of 3D Human Facial Images from DNA Sequence
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao+11 more
wiley +1 more source
Is the Zika virus re-emerging as a distinct genetic lineage in India? [PDF]
Kumar N P+14 more
europepmc +1 more source
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi+20 more
wiley +1 more source