Results 51 to 60 of about 256,534 (295)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Broadband multifunctional polarization converter based on graphene and vanadium dioxide metasurfaces along with analytical methods

Scientific Reports
In this paper, a tunable broadband multifunctional polarization converter based on graphene and vanadium dioxide (VO2) is designed. When VO2 is in the metallic state, the structure has the functions of three-band linear to linear and two-band linear to ...
Saman Heidari, Najmeh Nozhat
doaj   +1 more source

A Broadband High Gain Circularly Polarized Antenna System for Cognitive Radio [PDF]

Radioengineering, 2020
This paper proposes a broadband high gain LHCP (left hand circular polarized) antenna system using a microstrip line fed slot antenna, reflecting surfaces, and linear polarization (LP) to circular polarization (CP) transformer screen.
R. K. Parida, R. Swain, D. C. Panda, R. K. Mishra   +3 more
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Artificially anisotropic cylinder to convert omnidirectional linear polarization into circular polarization [PDF]

, 2017
Circular polarization and omnidirectional radiation are desired characteristics in various mobile communication systems. This paper studies possibilities to convert linear polarization into circular polarization by designing an artificially anisotropic ...
Berg, M. (Markus), Salonen, E. (Erkki), Kaivanto, E. (Emmi)   +2 more
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A Wideband Multi-Polarized Microstrip Antenna with High Polarization Isolation Based on Dual-Circular Polarization

Micromachines
To address the limited overlapping bandwidth across polarization modes in conventional multi-polarized antennas, this paper proposes a wideband multi-polarized microstrip antenna with high polarization isolation.
Xuenan Wang, Hongcheng Zhou, Xinhui Wang, Xia Lei, Boyang Hao, Mian Zhong, Chao Zhou   +6 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A Multi-Polarization Series-Fed Antenna Array Based on Eccentric Ring

IEEE Access, 2023
A multi-polarization series-fed antenna working at 10 GHz is presented in this paper. The patch elements are built by eccentric rings which can realize the performance of circular polarization.
Xin Guan, Zhenghui Xue, Wu Ren, Weiming Li   +3 more
doaj   +1 more source

Estimation of the Degree of Polarization for Hybrid/Compact and Linear Dual-Pol SAR Intensity Images: Principles and Applications [PDF]

, 2013
Analysis and comparison of linear and hybrid/compact dual-polarization (dual-pol) synthetic aperture radar (SAR) imagery have gained a wholly new importance in the last few years, in particular, with the advent of new spaceborne SARs such as the Japanese
Shirvany, Reza, Chabert, Marie, Tourneret, Jean-Yves   +2 more
core   +1 more source