Results 221 to 230 of about 5,206,546 (317)

Age-specific patterns of lymph node involvement in elderly patients with oral squamous cell carcinoma: a retrospective cohort study. [PDF]

Clin Oral Investig
Schmitz AM, Kern N, Brauckmann M, Hofmann C, Mrosk F, Rendenbach C, Doll C, Richter M, Heiland M, Koerdt S.   +9 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A generalized logistic-logit function and its application to multi-layer perceptron and neuron segmentation. [PDF]

Front Artif Intell
Gu W, Zhang Y, Muscoloni A, Cannistraci CV.   +3 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Linear Orders

Proceedings of the National Academy of Sciences, 1937
openaire   +4 more sources

Heads of Sci-Tech Libraries

Issues in Science and Technology Librarianship, 1999
Pat Kreitz
doaj   +1 more source

Constructing targeted minimum loss/maximum likelihood estimators: a simple illustration to build intuition. [PDF]

Am J Epidemiol
Ross RK, Montoya LM, Goin DE, Díaz I, Renson A.   +4 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

<i>Paecilomyces variotii</i> Mycoprotein in Diets for Juvenile Rainbow Trout: Effects on Growth Performance, Intestinal Health and Technical Feed Quality. [PDF]

Aquac Nutr
Gaudhaman A, Vidakovic A, Warwas N, Doyle D, Morales-Lange B, Øverland M, Lundh T, Baruah K.   +7 more
europepmc   +1 more source