Results 131 to 140 of about 3,120,215 (305)

Accelerator modeling system for the future [PDF]

, 1994
Many computer programs and a variety of models exist for the design of accelerator lattices and the correction of errors. Many physicists contributed to this work by developing codes to suit a variety of machines.
Lee, M., Cai, Y., Tran, P.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

An Estimated Small Open Economy Model of the Financial Accelerator [PDF]

This paper develops a small open economy model in which entrepreneurs partially finance investment using foreign currency-denominated debt subject to an external finance premium. We use Bayesian estimation techniques to evaluate the importance of balance
Selim Elekdag, Ivan Tchakarov, Alejandro Justiniano   +2 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

150-MW S-band klystron program at the Stanford Linear Accelerator Center [PDF]

, 1996
Two S-Band klystrons operating at 150 MW have been designed, fabricated and tested at the Stanford Linear Accelerator Center (SLAC) during the past two years for use in an experimental accelerator at Deutsches Elektronen-Synchrotron (DESY) in Hamburg ...
Sprehn, D., Phillips, R M, Sprehn, D, Phillips, R. M., Caryotakis, G, Caryotakis, G.   +5 more
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Coherent pair creation as a positron source for linear colliders [PDF]

, 1992
We propose a positron source for future linear colliders which uses the mechanism of coherent pair creation process from the collision of a high energy electron beam and a monochromatic photon beam.
Palmer, R.B. (Stanford Linear Accelerator Center, Menlo Park, CA (United States) Brookhaven National Lab., Upton, NY (United States)), Chen, P. (Stanford Linear Accelerator Center, Menlo Park, CA (United States))   +1 more
core  

Beam-based identification of magnetic field errors in a synchrotron using deep Lie map networks

Physical Review Accelerators and Beams
We report on the recovery of both linear and nonlinear optics in a hadron synchrotron using the novel deep Lie map network (DLMN) approach. The DLMN enables the construction of a detailed accelerator model by integrating charged particle dynamics with ...
Conrad Caliari, Adrian Oeftiger, Oliver Boine-Frankenheim   +2 more
doaj   +1 more source