Results 91 to 100 of about 172,072 (313)
Approximate Kalman filtering by both M-robustified dynamic stochastic approximation and statistical linearization methods [PDF]
, 2023 Miloš Pavlović +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A finite element/polynomial spectral mixed approximation for the Stokes problem
Results in Applied MathematicsA mixed Galerkin approximation for the Stokes problem is proposed. The finite element approximation is used for the velocity and the polynomial spectral approximation for pressure.
Shinya Uchiumi
doaj +1 more source
Piecewise linear approximation methods with stochastic sampling sites
Journal of Computational and Applied Mathematics, 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Junbin Li +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Θ-transformation of certain positive linear operators
International Journal of Mathematics and Mathematical Sciences, 1996 The intention of this paper is to describe a construction method for a new sequence of linear positive operators, which enables us to get a pointwise order of approximation regarding the polynomial summator operators which have best properties of ...
Aleandru Lupaş, Detlef H. Mache
doaj +1 more source
A Linear Approximation Method for Probabilistic Inference [PDF]
, 1990 An approximation method is presented for probabilistic inference with continuous random variables. These problems can arise in many practical problems, in particular where there are “second order” probabilities. The approximation, based on the Gaussian influence diagram, iterates over linear approximations to the inference problem.
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source