Results 121 to 130 of about 172,072 (313)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Stabilizer-free weak Galerkin finite element for linear elastic problems
Linear elastic problem originates from engineering applications such as machinery and aviation.Due to the complexity of differential equation in the linear elastic problem, the analytic solutions of the problem are still unknown.Although the classical ...
XU Yue, CHEN Yumei, XIE Xiaoping
doaj
Reconstruction of Mixed Boundary Objects and Classification Using Deep Learning and Linear Sampling Method [PDF]
The linear sampling method is a simple and reliable linear inversion technique for determining the morphological features of unknown objects under investigation.
S. B. Harisha, E. Mallikarjun, M. Amit
doaj
Padé approximation and linear prediction methods [PDF]
J. TANG, J. R. NORRIS
openaire +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source

