Results 51 to 60 of about 172,072 (313)

A quantum algorithm for linear autonomous differential equations via Padé approximation [PDF]

open access: yesQuantum
We propose a novel quantum algorithm for solving linear autonomous ordinary differential equations (ODEs) using the Padé approximation. For linear autonomous ODEs, the discretized solution can be represented by a product of matrix exponentials.
Dekuan Dong, Yingzhou Li, Jungong Xue
doaj   +1 more source

Effective Activation Functions for Homomorphic Evaluation of Deep Neural Networks

open access: yesIEEE Access, 2020
CryptoNets and subsequent work have demonstrated the capability of homomorphic encryption (HE) in the applications of private artificial intelligence (AI).
Srinath Obla   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Incremental Non-Linear Manifold Approximation Method

open access: yesCoRR
19 ...
Praveen T. W. Hettige, Benjamin W. Ong
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

B‐splines image approximation using resampled chordal parameterization

open access: yesIET Image Processing
Image processing often requires filtering, which can be effectively performed by using B‐spline surface approximation. This article presents a fast method of approximating data in rectangular (image) form using such surfaces. The method considers dynamic
Robert Świta, Zbigniew Suszyński
doaj   +1 more source

Approaches to enthalpy approximation in numerical simulation of two-component alloy solidification

open access: yesComputer Assisted Methods in Engineering and Science, 2023
The paper deals with the numerical modelling of solidification of two- component metal alloys. The numerical model was worked out using the enthalpy formulation of solidification and the finite element method.
Norbert Sczygiol
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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