Results 51 to 60 of about 55,053 (254)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Investigation of polymer-based BaO and rGO nanocomposites for application in low energy X ray attenuation

Brazilian Journal of Radiation Sciences, 2019
Polymeric materials can serve as a matrix for the dispersion of nanomaterials with good attenuation features, resulting in lightweight, conformable, flexible, lead-free and easy-to-process materials.
LILIANE Aparecida SILVA, adriana Batistab, Jefferson Nascimentoc, Clascidia Furtadoc, Luiz Faria   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Monte Carlo Probability To Determine Attenuation Coefficient In Identifying The Selectivity Properties Of Near-Infrared-Based Materials

Protek: Jurnal Ilmiah Teknik Elektro
Accurate attenuation coefficient measurements are able to display the nature of selectivity in an image. The methods used to measure the attenuation coefficient are Monte Carlo probability and linear regression models.
Rovika Trioclarise, Toto Aminoto, Yoni Rutiana Kusumawati, Ratu Karel lina   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Evaluation of a Metal-Organic Composite (Tungsten-Lignin) for Attenuation of Gamma Radiation [PDF]

Materials Research, 2019
The objective of this work was to use tungsten and lignin as precursors to obtain a metal-organic composite tungsten-lignin (W-Lig) using different sintering temperatures.
Armando Cirilo de Souza, Francisco Carlos Cione, Aline Cardoso da Silva, Adriana de Fátima Gomes Gouvêa, Noé Gabriel Pinheiro Machado, Marcus Paulo Raele, Jesualdo Luiz Rossi   +6 more
doaj   +1 more source

Near K-edge linear attenuation coefficients for amorphous and crystalline GaAs [PDF]

Radiation Physics and Chemistry, 2003
Abstract We present tabulated near K-edge linear attenuation coefficients for stoichiometric crystalline and amorphous gallium arsenide. The coefficients were derived from total electron yield photocurrent measurements at the Daresbury Synchrotron Radiation Source and show considerable near-edge structure when compared to curves generated from ...
Alan Owens, J.F.W Mosselmans, A Peacock
openaire   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source