Results 151 to 160 of about 7,931,944 (349)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Advances in Civil and Architectural EngineeringThe substructure of a berthing structure with a deep draft presents significant financial challenges. This research offers valuable perspectives on minimizing substructure expenses for a berthing structure by leveraging the Indian Standard (IS) code for ...
Namratha Sasikumar +2 more
doaj +1 more source
Variant code transformations for linear quadtrees
, 2020 In this paper, general guidelines and specific algorithms for code transformations between breadth-first (BF) and depth-first (DF) linear quadtrees are proposed. Each algorithm has time and space complexities in OðlÞ, where l is the length of the code of
Pei-Min Chen
core
Global Model Multiple Linear Regression Code
, 2019 Code for the global models for the multiple linear regression analyses (torpor duration and depth)
Nicole Besler (7071512) +3 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
GEOMETRIC CONSTRUCTION CODES OF HAMMING DISTANCE-8
Electrica, 2008 A new high rate binary linear block code construction technique, named as Geometric Construction (GC) codes, was proposed recently [1]. It generates all the even full information rate (optimal) Hamming distance – 4 codes.
Gökmen Altay
doaj +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Full-Diversity Space-Time Error Correcting Codes with Low-Complexity Receivers
EURASIP Journal on Wireless Communications and Networking, 2011 We propose an explicit construction of full-diversity space-time block codes, under the constraint of an error correction capability. Furthermore, these codes are constructed in order to be suitable for a serial concatenation with an outer linear ...
Hassan MohamadSayed, Amis Karine
doaj
Appendix 5: Bayesian linear model code
, 2015 R script containing code to run Bayesian linear model.
Clark, Robert G. +9 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source