Results 41 to 50 of about 2,120,403 (275)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Algorithms, 2019 A generalization of Ding’s construction is proposed that employs as a defining set the collection of the sth powers ( s ≥ 2 ) of all nonzero elements in G F ( p m ) , where p ≥ 2 is prime.
Dean Crnković +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Optimal Quaternary Hermitian LCD Codes
EntropyLinear complementary dual (LCD) codes, which are a class of linear codes introduced by Massey, have been extensively studied in the literature recently.
Liangdong Lu, Ruihu Li, Yuezhen Ren
doaj +1 more source
Linear-time general decoding algorithm for the surface code
, 2018 A quantum error correcting protocol can be substantially improved by taking into account features of the physical noise process. We present an efficient decoder for the surface code which can account for general noise features, including coherences and ...
Darmawan, Andrew S., Poulin, David
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Fuzzy linear codes based on nested linear codes
Fuzzy Sets and Systems, 2023 In this paper, we describe a correspondence between a fuzzy linear code and a family of nested linear codes. We also describe the arithmetic of fuzzy linear codes. As a special class of nested linear codes, we consider a family of nested self-orthogonal codes.
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Linear-Codes-Based Lossless Joint Source-Channel Coding for Multiple-Access Channels
, 2009 A general lossless joint source-channel coding (JSCC) scheme based on linear codes and random interleavers for multiple-access channels (MACs) is presented and then analyzed in this paper.
Chen, Yan +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source