Results 131 to 140 of about 236,875 (314)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Machine learning discovers new champion codes

npj Artificial Intelligence
Linear error-correcting codes form the mathematical backbone of modern digital communication and storage systems, but identifying champion linear codes (linear codes achieving or exceeding the best known minimum Hamming distance) remains challenging.
Yang-Hui He, Alexander M. Kasprzyk, Q Le, Dmitrii Riabchenko   +3 more
doaj   +1 more source

Low-density parity-check codes and their rateless relatives

, 2011
This survey guides the reader through the extensive open literature that is covering the family of low-density parity-check LDPC codes and their rateless relatives.
Sheng Chen, Chen, Sheng, Nicholas Bonello, Bonello, Nicholas, Hanzo, Lajos, Lajos Hanzo   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Lower Bound on the Success Probability of Binary Random Linear Network Codes Aided by Noise Decoding

IEEE Open Journal of the Communications Society
The decoding of binary random linear codes for packet erasures relies on receivers collecting a sufficient number of error-free coded packets for the reconstruction of a transmitted message.
Ioannis Chatzigeorgiou
doaj   +1 more source

RS + LDPC-Staircase Codes for the Erasure Channel: Standards, Usage and Performance [PDF]

, 2013
Application-Level Forward Erasure Correction (AL-FEC) codes are a key element of telecommunication systems. They are used to recover from packet losses when retransmission are not feasible and to optimize the large scale distribution of contents. In this
Detchart, Jonathan, Thiénot, Cédric, Lacan, Jérôme, Cunche, Mathieu, Roca, Vincent   +4 more
core  

Xing–Ling codes, duals of their subcodes, and good asymmetric quantum codes

, 2013
A class of powerful q-ary linear polynomial codes originally proposed by Xing and Ling is deployed to construct good asymmetric quantum codes via the standard CSS construction.
Ezerman, Martianus Frederic, Solé, Patrick, Jitman, Somphong   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The c-Differential-Linear Connectivity Table of Vectorial Boolean Functions

Entropy
Vectorial Boolean functions and codes are closely related and interconnected. On the one hand, various requirements of binary linear codes are needed for their theoretical interests but, more importantly, for their practical applications (such as few ...
Said Eddahmani, Sihem Mesnager
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source