Results 51 to 60 of about 1,005,908 (254)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Simple Rate-1/3 Convolutional and Tail-Biting Quantum Error-Correcting Codes
Simple rate-1/3 single-error-correcting unrestricted and CSS-type quantum convolutional codes are constructed from classical self-orthogonal $\F_4$-linear and $\F_2$-linear convolutional codes, respectively.
Forney, Jr., G. David, Guha, Saikat
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Linear codes over a general infinite family of rings and MacWilliams-type relations [PDF]
Irwansyah, Djoko Suprijanto
doaj +1 more source
Transformation of Binary Linear Block Codes to Polar Codes With Dynamic Frozen
In this paper, a general transformation of binary linear block codes (BLBCs) to (possibly, multi-kernel) polar codes with dynamic frozen bits is proposed.
Chien-Ying Lin +3 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Convolutional and tail-biting quantum error-correcting codes
Rate-(n-2)/n unrestricted and CSS-type quantum convolutional codes with up to 4096 states and minimum distances up to 10 are constructed as stabilizer codes from classical self-orthogonal rate-1/n F_4-linear and binary linear convolutional codes ...
Forney, Jr., G. David +2 more
core +2 more sources
Ultimate linear block and convolutional codes
Linear block and convolutional codes are designed using unit schemes and families of these to required length, rate, distance and type are mined. Properties, such as type and distance, of the codes follow from the types of units used and thus required ...
Ted Hurley
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

