Results 71 to 80 of about 1,011,482 (281)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Simplex Linear Codes Over the Ring F2 + vF2 [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2008 In this paper, we construct simplex linear codes over the ring of types , where and . We also determine some of their properties. These codes are extension and generalization of simplex codes over the rings .
Mohammed AL-Ashker, Ibtisam Isleem
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Linear codes over a general infinite family of rings and MacWilliams-type relations [PDF]
Discrete Mathematics Letters, 2022 Irwansyah, Djoko Suprijanto
doaj +1 more source
Self-Orthogonal Codes Constructed from Posets and Their Applications in Quantum Communication
Mathematics, 2020 It is an important issue to search for self-orthogonal codes for construction of quantum codes by CSS construction (Calderbank-Sho-Steane codes); in quantum error correction, CSS codes are a special type of stabilizer codes constructed from classical ...
Yansheng Wu, Yoonjin Lee
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Intersection of Isomorphic Linear Codes
Journal of Combinatorial Theory, Series A, 1997 Two \((n,k)\) linear codes are said to be isomorphic if there is a permutation of the coordinates that maps one code onto the other. The intersection of two isomorphic \((n,k)\) codes is an \((n,k')\) code, where clearly \(\max\{0,2k-n\}\leq k' \leq k\). In this paper, the problem of finding all attainable values of \(k'\), called intersection numbers,
Eli Bar-Yahalom, Tuvi Etzion
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source