Results 91 to 100 of about 216,076 (266)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Cyclic Codes over a Split Local Ring of Type (2,2): Structure, Gray Images, and Distance Analysis
MathematicsWe study cyclic codes over split two-branch finite local rings of the form Rl,m=Fp[u,v]/⟨ul,vm,uv⟩,l,m≥2, whose radical filtration is governed by two independent nilpotent chains: u→u2→⋯→ul−1→0andv→v2→⋯→vm−1→0.
Sami H. Saif, Alhanouf Ali Alhomaidhi
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Machine learning discovers new champion codes
npj Artificial IntelligenceLinear error-correcting codes form the mathematical backbone of modern digital communication and storage systems, but identifying champion linear codes (linear codes achieving or exceeding the best known minimum Hamming distance) remains challenging.
Yang-Hui He +3 more
doaj +1 more source
IEEE Open Journal of the Communications SocietyThe decoding of binary random linear codes for packet erasures relies on receivers collecting a sufficient number of error-free coded packets for the reconstruction of a transmitted message.
Ioannis Chatzigeorgiou
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The c-Differential-Linear Connectivity Table of Vectorial Boolean Functions
EntropyVectorial Boolean functions and codes are closely related and interconnected. On the one hand, various requirements of binary linear codes are needed for their theoretical interests but, more importantly, for their practical applications (such as few ...
Said Eddahmani, Sihem Mesnager
doaj +1 more source