Results 81 to 90 of about 1,011,482 (281)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linear Skew Cyclic Codes over 𝔽qS

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
In this study, we focus on skew cyclic codes over the family of rings 𝔽q S where q is a power of a prime number and S = 𝔽q + v𝔽q with v2 = v. Structural properties of these codes are studied in detail. Obtained results lead us to characterize 𝔽q S-linear
Yildirim Tulay
doaj   +1 more source

Efficient and low-complexity matrix inversion scheme for massive multiple-input multiple-output systems using rapid numerical algorithms

open access: yesThe Journal of Engineering, 2019
Performances of the regularised zero forcing (RZF) precoder, rapid numerical algorithm (RNA) precoder and the truncated polynomial expansion (TPE) Precoder are compared and analysed for massive multiple-input multiple-output (MIMO) wireless system in a ...
Emmanuel Mukubwa, Oludare A. Sokoya
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Two Classes of Linear Codes From Weil Sums

open access: yesIEEE Access, 2020
In this article, we consider two classes of $p$ -ary linear codes. This article is a generalization of the recent construction methods given by Jian, Lin and Feng (2019).
Hong Lu, Shudi Yang
doaj   +1 more source

A linear construction for certain Kerdock and Preparata codes

open access: yes, 1993
The Nordstrom-Robinson, Kerdock, and (slightly modified) Pre\- parata codes are shown to be linear over $\ZZ_4$, the integers $\bmod~4$. The Kerdock and Preparata codes are duals over $\ZZ_4$, and the Nordstrom-Robinson code is self-dual. All these codes
A. R. Calderbank   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LCD codes and LCP of codes from units of group rings

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
A linear code with complementary dual(LCD) is a linear code such that LCD codes are of greatimportance due to their wide range of applications in consumer electronics,storage systems and cryptography. Group rings have a rich source of units. Alsothe well-
Mehmet Emin Köroğlu
doaj   +1 more source

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