Results 141 to 150 of about 1,048,571 (242)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A Comparative Study of A₂SiF₆ (A = Cs, K) Phosphor Host Matrices: Linear Combination of Atomic Orbital Hybrid Density Functional Theory Calculations. [PDF]

Materials (Basel)
Rusevich LL, Brik MG, Gryaznov D, Srivastava AM, Chervyakov ID, Zvejnieks G, Bocharov D, Kotomin EA.   +7 more
europepmc   +1 more source

MULTIVARIATE LINEAR CALIBRATION FOR LINEAR COMBINATIONS

MULTIVARIATE LINEAR CALIBRATION FOR LINEAR COMBINATIONS
This paper discusses confidence regions of linear combinations of explanatory variables in multivariate linear calibration. Approximated confidence regions are considered, since the exact confidence regions in multivariate linear calibration are often empty or are not bounded. A numerical example is given for the approximated confidence regions.
openaire  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

First-Principles Linear Combination of Atomic Orbitals Calculations of K₂SiF₆ Crystal: Structural, Electronic, Elastic, Vibrational and Dielectric Properties. [PDF]

Materials (Basel)
Rusevich LL, Brik MG, Gryaznov D, Srivastava AM, Chervyakov I, Zvejnieks G, Bocharov D, Kotomin EA.   +7 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Wildlife habitat suitability analysis and mapping the former dhidhessa wildlife sanctuary using GIS-based analytical hierarchal process and weighted linear combination methods. [PDF]

Heliyon
Edosa BT, Erena MG.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

A Fine Analysis of Zn Species Structure and Distribution in Zn/ZSM-5 Catalysts by Linear Combination Fitting Analysis of XANES Spectra. [PDF]

Molecules
Li B, Gao J, Shao J, Geng R, Qin Z, Wang J, Fan W, Dong M.   +7 more
europepmc   +1 more source