Results 51 to 60 of about 105,781 (281)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A full-modified-Newton step infeasible interior-point method for monotone linear complementarity problem

open access: yesپژوهش‌های ریاضی, 2021
By using a new search direction, we propose an infeasible interior-point method for monotone linear complementarity problem. The algorithm uses only one feasibility step in each iteration, and we prove that it suffices in order to obtain a polynomial ...
Nezameddin Mahdavi-Amiri   +1 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A Full-Newton step infeasible-interior-point algorithm for P*(k)-horizontal linear complementarity problems [PDF]

open access: yesYugoslav Journal of Operations Research, 2015
In this paper we generalize an infeasible interior-point method for linear optimization to horizontal linear complementarity problem (HLCP). This algorithm starts from strictly feasible iterates on the central path of a perturbed problem that is
Asadi S., Mansouri H.
doaj   +1 more source

On degeneracy in linear complementarity problems

open access: yesDiscrete Applied Mathematics, 1985
This paper presents a method for handling degeneracy in linear complementarity problems. The method is based on the sequential (variable-dimension) version of Lemke's algorithm. Curiously, the paper makes no mention of other publications pertaining to degeneracy handling in Lemke's method or any other.
openaire   +2 more sources

Robustness and nondegenerateness for linear complementarity problems [PDF]

open access: yesMathematical Programming, 1987
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jansen, M.J.M., Tijs, S.H.
openaire   +4 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Projective algorithms for solving complementarity problems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
We present robust projective algorithms of the von Neumann type for the linear complementarity problem and for the generalized linear complementarity problem.
Caroline N. Haddad, George J. Habetler
doaj   +1 more source

Projection and Contraction Method for Pricing American Bond Options

open access: yesMathematics, 2023
In this paper, an effective numerical method is proposed for a linear complementarity problem (LCP) arising in the valuation of American bond options under the Cox–Ingersoll–Ross (CIR) model.
Qi Zhang   +4 more
doaj   +1 more source

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