Results 111 to 120 of about 20,201,183 (253)

SUBSPACE IDENTIFICATION METHOD FOR STOCHASTIC LINEAR CONTROL SYSTEMS

Ural Mathematical Journal
Subspace identification is studied for stochastic linear control systems in state-space form. PO-MOESP (Past Outputs Multivariable Output-Error State sPace) algorithm is described, implemented and compared with other subspace identification methods and ...
Nikita M. Kharkovskii, Nikolai B. Melnikov   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Point to point control of fractional differential linear control systems

Advances in Difference Equations, 2011
In the article, an alternative elementary method for steering a controllable fractional linear control system with open-loop control is presented. It takes a system from an initial point to a final point in a state space, in a given finite time interval.
Dzieliński Andrzej, Malesza Wiktor
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Event–Based Feedforward Control of Linear Systems with input Time–Delay

International Journal of Applied Mathematics and Computer Science, 2019
This paper proposes a new method for the analysis of continuous and periodic event-based state-feedback plus static feed-forward controllers that regulate linear time invariant systems with time delays.
Rodríguez Carlos, Aranda-Escolástico Ernesto, Guinaldo María, Guzmán José Luis, Dormido Sebastián   +4 more
doaj   +1 more source

The Chain Control Set of a Linear Control System

SIAM Journal on Control and Optimization
In this paper, we analyze the chain control sets of linear control systems on connected Lie groups. Our main result shows that the compactness of the central subgroup associated with the drift is a necessary and sufficient condition to assure the uniqueness and compactness of the chain control set.
openaire   +4 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Multi-objective controller design for bi-linear stochastic systems via sliding mode control concept

, 2012
[[abstract]]A sliding mode controller u(t) is designed to achieve the following three objectives simultaneously: eigenvalue placement, H‘ norm constraint, and individual state variance constraint for bi-linear stochastic systems.
Chang, K. Y. ; Lu, Chien-Yu; Shih, C. H. ; Chen, P. C.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source