Results 131 to 140 of about 25,937,483 (340)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Neither Zero nor Hold: Optimal Linear-Quadratic-Regulator State-Feedback Control Over Lossy Networks
IEEE AccessThis paper addresses the networked control design problem in which control packets are subject to dropout. We present an alternative to the two most straightforward compensation strategies available in the literature: the zero-input and hold-input ...
Caio Toledo Dutra Santos +2 more
doaj +1 more source
Resilient Stabilization of Switched Linear Control Systems Against Adversarial Switching
IEEE Transactions on Automatic Control, 2017 Jianghai Hu, Jinglai Shen, Donghwan Lee
semanticscholar +1 more source
Linear quadratic control for networked control systems with information limitations
, 2016 This paper investigates the minimum information rate for linear quadratic (LQ) control of stochastic linear systems, where the sensors and controllers are geographically separated and connected via noiseless, bandwidth-limited digital communication ...
Liu QQ(刘庆泉), Jin F(金芳)
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Solutions of linear control systems on Lie groups
Open MathematicsAn explicit solution for linear control systems on Lie groups is presented using the variation of parameters method. This solution is formulated as a series of Lie brackets, and the convergence of these series is analyzed.
Ayala Victor +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
LMI based stability analysis and robust controller design for discrete linear repetitive processes
, 2003 Discrete linear repetitive processes are a distinct class of 2D linear systems with applications in areas ranging from long-wall coal cutting through to iterative learning control schemes.
Owens, D H +7 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source