Results 61 to 70 of about 5,335,458 (280)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

On a representation of linear differential equations

open access: yesMathematical and Computer Modelling, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Linear Analysis of an Integro-Differential Delay Equation Model

open access: yesInternational Journal of Differential Equations, 2018
This paper presents a computational study of the stability of the steady state solutions of a biological model with negative feedback and time delay. The motivation behind the construction of our system comes from biological gene networks and the model ...
Anael Verdugo
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Euler Type Half-Linear Differential Equation with Periodic Coefficients

open access: yesAbstract and Applied Analysis, 2013
We investigate oscillatory properties of the perturbed half-linear Euler differential equation. We show that the results of the recent paper by O. Došlý and H.
Ondřej Došlý, Hana Funková
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Local estimates for modified Riccati equation in theory of half-linear differential equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper we study the half-linear differential equation \begin{equation*} \bigl(r(t)\Phi_p(x')\bigr)'+c(t)\Phi_p(x)=0, \end{equation*} where $\Phi_p(x)=|x|^{p-2}x$, $p>1$. Using modified Riccati technique and suitable local estimates for terms
Simona Fišnarová, Robert Marik
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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