Results 71 to 80 of about 5,049,567 (284)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Input-to-State Stability of Linear Stochastic Functional Differential Equations
The purpose of the paper is to show how asymptotic properties, first of all stochastic Lyapunov stability, of linear stochastic functional differential equations can be studied via the property of solvability of the equation in certain pairs of spaces of
Ramazan Kadiev, Arcady Ponosov
doaj +1 more source
Wavelets based physics informed neural networks to solve non-linear differential equations. [PDF]
Uddin Z, Ganga S, Asthana R, Ibrahim W.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Optimal Hyers-Ulam’s constant for the linear differential equations
In this paper, we will obtain the optimal Hyers-Ulam’s constant for the first-order linear differential equations p ( t ) y ′ ( t ) − q ( t ) y ( t ) − r ( t ) = 0 $p(t)y'(t) - q(t)y(t) - r(t) = 0$ .
Soon-Mo Jung, Jaiok Roh, Juri Lee
doaj +1 more source
On the Stability and Null-Controllability of an Infinite System of Linear Differential Equations. [PDF]
Azamov A +3 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Regularization of non-linear measure differential equations
The Cauchy problem for a non-linear system of regularized measure differential equations is studied. It is proved that the solutions of the regularized problems converges to a solution of an integral equation involving measures.
Jan Persson
doaj
Simple Equations Method and Non-Linear Differential Equations with Non-Polynomial Non-Linearity. [PDF]
Vitanov NK, Dimitrova ZI.
europepmc +1 more source

