Results 71 to 80 of about 103,833 (268)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Regularization of non-linear measure differential equations
Le Matematiche, 1989 The Cauchy problem for a non-linear system of regularized measure differential equations is studied. It is proved that the solutions of the regularized problems converges to a solution of an integral equation involving measures.
Jan Persson
doaj
Simple Equations Method and Non-Linear Differential Equations with Non-Polynomial Non-Linearity. [PDF]
Entropy (Basel), 2021 Vitanov NK, Dimitrova ZI.
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Lyapunov-type inequalities for third-order linear differential equations
Electronic Journal of Differential Equations, 2017 In this article, we establish new Lyapunov-type inequalities for third-order linear differential equations $$ y'''+q( t) y=0, $$ under the three-point boundary conditions $$ y( a) =y( b) =y( c) =0 $$ and $$ y( a) =y''( d) =y( b) =0 $$ by ...
Mustafa Fahri Aktas, Devrim Cakmak
doaj
Optimal Hyers-Ulam’s constant for the linear differential equations
Journal of Inequalities and Applications, 2016 In this paper, we will obtain the optimal Hyers-Ulam’s constant for the first-order linear differential equations p ( t ) y ′ ( t ) − q ( t ) y ( t ) − r ( t ) = 0 $p(t)y'(t) - q(t)y(t) - r(t) = 0$ .
Soon-Mo Jung, Jaiok Roh, Juri Lee
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source