Results 31 to 40 of about 3,374 (246)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Segregated direct boundary-domain integral equations (BDIEs) based on a parametrix and associated with the Dirichlet and Neumann boundary value problems for the linear stationary diffusion partial differential equation with a variable Hölder-continuous ...
Sergey E. Mikhailov
doaj +1 more source
On the covering dimension of the set of solutions of some nonlinear equations [PDF]
We prove an abstract theorem whose sole hypothesis is that the degree of a certain map is nonzero and whose parametric equations are studied using cohomological mconclusions imply sharp, multidimensional continuation results.
Pejsachowicz, Jacobo +4 more
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Monotone iterative method for abstract impulsive integro-differential equations with nonlocal conditions in Banach spaces [PDF]
summary:In this paper we use a monotone iterative technique in the presence of the lower and upper solutions to discuss the existence of mild solutions for a class of semilinear impulsive integro-differential evolution equations of Volterra type with ...
Li, Yongxiang +3 more
core +1 more source
Nonlocal semilinear second-order differential inclusions in abstract spaces without compactness [PDF]
summary:We study the existence of a mild solution to the nonlocal initial value problem for semilinear second-order differential inclusions in abstract spaces.
Pavlačková, Martina, Taddei, Valentina
core +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Direct and inverse problems for linear relations
Direct and inverse problem related to linear differential inclusions in Banach spaces are studied.The abstract results are applied to degenerate partial dierential equations of parabolic type.
Angelo Favini
doaj

