Results 41 to 50 of about 192,670 (225)

Least Squares Ranking on Graphs [PDF]

open access: yes, 2011
Given a set of alternatives to be ranked, and some pairwise comparison data, ranking is a least squares computation on a graph. The vertices are the alternatives, and the edge values comprise the comparison data.
Hirani, Anil N.   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Petrov-Galerkin Method and Chebyshev Multiwavelet Basis for Solving Integro-Differential Equations

open access: yesInternational Journal of Industrial Engineering and Production Research, 2007
: There are some methods for solving integro-differential equations. In this work, we solve the general-order Feredholm integro-differential equations. The Petrov-Galerkin method by considering Chebyshev multiwavelet basis is used.
k. Maleknejad, M. Rabbani
doaj  

Scattering forms and the positive geometry of kinematics, color and the worldsheet

open access: yesJournal of High Energy Physics, 2018
The search for a theory of the S-Matrix over the past five decades has revealed surprising geometric structures underlying scattering amplitudes ranging from the string worldsheet to the amplituhedron, but these are all geometries in auxiliary spaces as ...
Nima Arkani-Hamed   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Operator splitting for dissipative delay equations

open access: yes, 2016
We investigate Lie-Trotter product formulae for abstract nonlinear evolution equations with delay. Using results from the theory of nonlinear contraction semigroups in Hilbert spaces, we explain the convergence of the splitting procedure.
Bátkai, András   +2 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A practical framework for infinite-dimensional linear algebra

open access: yes, 2014
We describe a framework for solving a broad class of infinite-dimensional linear equations, consisting of almost banded operators, which can be used to resepresent linear ordinary differential equations with general boundary conditions.
Olver, Sheehan, Townsend, Alex
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

A variational approach to strongly damped wave equations

open access: yes, 2007
We discuss a Hilbert space method that allows to prove analytical well-posedness of a class of linear strongly damped wave equations. The main technical tool is a perturbation lemma for sesquilinear forms, which seems to be new.
A. Bátkai   +23 more
core   +2 more sources

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