Results 131 to 140 of about 24,268,118 (293)

Models selected for linear discriminant function analysis.

open access: yes, 2018
Models selected for linear discriminant function analysis.
Elisabeth B. Webb (468956)   +4 more
core   +1 more source

Non‐Covalent Reversibly Photoconvertible Fluorescent Tags for Wash‐Free Protein Labeling

open access: yesAdvanced Science, EarlyView.
FAST proteins combined with one or two fluorogens undergo reversible fluorescence switching or photoconversion through photoisomerization. At low fluorogen concentration and high light intensity, they act as negative or positive photoswitchers and photoconvertible tags, which are promising for discriminating FAST variants.
Mrinal Mandal   +12 more
wiley   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

open access: yesAdvanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu   +8 more
wiley   +1 more source

Combining Feature Extraction Methods and Categorical Boosting to Discriminate the Lettuce Storage Time Using Near-Infrared Spectroscopy

open access: yesFoods
Lettuce is a kind of nutritious leafy vegetable. The lettuce storage time has a significant impact on its nutrition and taste. Therefore, to classify lettuce samples with different storage times accurately and non-destructively, this study built ...
Xuan Zhou   +3 more
doaj   +1 more source

Recognizing mathematical talent : an approach using discriminant analysis [PDF]

open access: yes
The aim of this paper is to extract mathematically talented students out of a group of arbitrary high school students. We do this by applying a stepwise discriminant analysis modified for ordinal data to the results of German high school students at the ...
Sibbertsen, Philipp, Gebel, Meike
core  

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

open access: yesAdvanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu   +13 more
wiley   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

open access: yesAdvanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji   +11 more
wiley   +1 more source

Normalization discriminant independent component analysis

open access: yes, 2013
In face recognition, feature extraction techniques attempts to search for appropriate representation of the data. However, when the feature dimension is larger than the samples size, it brings performance degradation.
Liew, Yee Ping   +4 more
core   +1 more source

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