Results 71 to 80 of about 2,103,936 (264)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
International Journal of COPD, 2016 Cássia Da Luz Goulart,1 Julio Cristiano Simon,1 Paloma De Borba Schneiders,1 Elisabete Antunes San Martin,1 Ramona Cabiddu,2 Audrey Borghi-Silva,2 Renata Trimer,2 Andréa Lúcia Gonçalves da Silva1 1Course of Physiotherapy ...
Goulart CL +7 more
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Quantifying Reserve Uncertainty Using Stochastic Multivariate Generalized Linear Model: A Case Study on Egyptian General Insurance Market [PDF]
Maǧallaẗ Al-Buḥūṯ Al-Mālīyyaẗ wa Al-TiğāriyyaẗAccurate claims reserving is crucial for insurance companies as it directly influences risk assessment, pricing strategies, and overall financial position. Traditional univariate reserving approaches, which treat each line of business independently, fail
شانا يوسف عبدالله +2 more
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linemodels: clustering effects based on linear relationships
Bioinformatics, 2023 AbstractSummaryEstimation of effects of multiple explanatory variables on multiple outcome measures has become routine across life sciences with high-throughput molecular technologies. The linemodels R-package allows a probabilistic clustering of variables based on their observed effect sizes on two outcomes.Availability and implementationAn open ...
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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A New Approach to Detect Mover Position in Linear Motors Using Magnetic Sensors
Sensors, 2015 A new method to detect the mover position of a linear motor is proposed in this paper. This method employs a simple cheap Hall Effect sensor-based magnetic sensor unit to detect the mover position of the linear motor.
Sarbajit Paul, Junghwan Chang
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Effective Behavior on Multiple Linear Systems [PDF]
Asian Journal of Mathematics, 2004 Latex, 17 pages. Asian Journal of Mathematics (to appear)
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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