Results 131 to 140 of about 1,044,555 (313)

Extensional flow of Newtonian and Boger fluids through a flow focusing microdevice

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Alves, MA   +3 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Scaling Aspects of Lyari River Flow Routing [PDF]

open access: yes
In this communication we utilize an improved version for model proposed by Manning for the waste flow via an open channel Lyari. We have computed the status of discharges, storages and depth for all locations of the Lyari waste flow using this proposed ...
Asif Mansoor, Rana Khalid Naeem
core  

Linear actuator for a submersible water pump for use in boreholes [PDF]

open access: yes, 2007
Both the theory and the test results show that the E-core electromagnet linear actuator, which is based on the variable reluctance principle, can generate a normal force in excess of 400kNm(^-2) when there is a flux density of IT within the airgap.
Cain, Martin
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Linear Free Surface of Steady and Unsteady Flow Theoretical Study

open access: yesTikrit Journal of Pure Science
This study investigates the relationship between the crucial cone point in limiting steady and unsteady simulation flows inside a simple two-dimensional, vertical sand column subjected to water withdrawal.
Suha Ibrahim AL-Ali, Nihad Jalal AL-Awsi
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A robust and accurate Navier-Stokes algorithm for three-dimensional applications adopting arbitrary modelling of the Reynolds stresses [PDF]

open access: yes, 1999
In this thesis a new Navier-Stokes solver for complex three-dimensional geometries, adopting arbitrary modelling of the Reynolds stresses, is presented.
Botte, V., Botte, Vincenzo
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A non-linear perturbation model considering catchment wetness and its application in river flow forecasting

open access: yes, 1997
A non-linear perturbation model for river flow forecasting is developed, based on consideration of catchment wetness using an antecedent precipitation index (API). Catchment seasonality, of the form accounted for in the linear perturbation model (the LPM)
R.K. Kachroo   +4 more
core  

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