Results 111 to 120 of about 1,044,555 (313)
The cascade structure of linear instability in collapsible channel flows [PDF]
, 2008 This paper studies the unsteady behaviour and linear stability of the flow in a collapsible channel using a fluid–beam model. The solid mechanics is analysed in a plane strain configuration, in which the principal stretch is defined with a zero initial ...
W. G. LI +7 more
core +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Secondary flows and inlet skew in axial flow turbine cascades [PDF]
, 1987 This thesis presents a detailed experimental investigation of the effects of inlet skew on the secondary flows and losses in a linear cascade of high turning turbine rotor blades.
Walsh, J.A, Walsh, Joseph Anthony
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Stability of Two Axially Superposed Fluids of Different Viscosities between Two Rotating Cylinders
Journal of Applied Fluid Mechanics, 2016 The linear stability of two axially superposed immiscible fluids between two rotating coaxial cylinders is studied. The fluids are assumed to have equal density but different viscosities.
V. R. K. Raju
doaj
Modified Ricci flow on a principal bundle
, 2008 textLet M be a Riemannian manifold with metric g, and let P be a principal G-bundle over M having connection one-form a. One can define a modified version of the Ricci flow on P by fixing the size of the fiber.
Young, Andrea Nicole, 1979-
core
Two-phase flow patterns in turbulent flow through a dose diffusion pipe
, 2005 A numerical investigation is carried out for turbulent particle-laden flow through a dose diffusion pipe for a model reactor system. A Lagrangian Stochastic Monte-Carlo particle-tracking approach and the averaged Reynolds equations with a k-e turbulence ...
Tang, H +5 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Impact of Nonlinear Flow Regime on the Flow Rate in Fractal Fractures
FluidsGeometric properties of fractures, such as aperture and width, among others, significantly affect the fluid flow behaviors in fractured media. Previous studies have shown that fractures exhibit fractal properties.
Jianting Zhu
doaj +1 more source