Results 81 to 90 of about 3,143,739 (339)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
CT&F Ciencia, Tecnología & Futuro, 2006 Because of fluvial deposition or faulting, many reservoirs around the world may possess a long and narrow geometry in which linear flow is expected to take place once radial flow vanishes, if existed.
Freddy Escobar, Matilde Montealegre
doaj
Development of a Hydraulic Conical Valve for the Linearization of Flow
MachinesConventional throttling valves have non-linear flow characteristics. However, in precise processes of flow control requiring them, appropriate flow modulations are necessary to enable a linear flow response even under partial valve actuations. This paper
Suyambu Pandian Asok +3 more
doaj +1 more source
On the impossibility of solitary Rossby waves in meridionally unbounded domains
, 2018 Evolution of weakly nonlinear and slowly varying Rossby waves in planetary atmospheres and oceans is considered within the quasi-geostrophic equation on unbounded domains.
Gottwald, Georg A. +1 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Analyzing Linear Communication Networks using the Ribosome Flow Model
, 2015 The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases.
Margaliot, Michael +2 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Linear Expansion of Isotropic Brownian Flows
Electronic Communications in Probability, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cranston, Michael +2 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source