Results 81 to 90 of about 1,044,555 (313)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
CT&F Ciencia, Tecnología & Futuro, 2006 Because of fluvial deposition or faulting, many reservoirs around the world may possess a long and narrow geometry in which linear flow is expected to take place once radial flow vanishes, if existed.
Freddy Escobar, Matilde Montealegre
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Development of a Hydraulic Conical Valve for the Linearization of Flow
MachinesConventional throttling valves have non-linear flow characteristics. However, in precise processes of flow control requiring them, appropriate flow modulations are necessary to enable a linear flow response even under partial valve actuations. This paper
Suyambu Pandian Asok +3 more
doaj +1 more source
Endwall profiling for the reduction of secondary flow in turbines [PDF]
, 2003 This thesis describes investigations into the use of a technique for improving the efficiency of axial flow turbines. The flow in the turbine component of axial flow machines is complex, with a number of three-dimensional features.
Ingram, Grant Laidlaw, Ingram, Grant
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Optimal linear power flow for droop controlled islanded microgrid
International Journal of Electrical Power & Energy SystemsThe time of optimal planning and operation of islanded microgrid (IMG) can be minimized by modeling it as non-iterative mixed integer linear problem (MILP).
Ankit Uniyal +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source