Results 111 to 120 of about 3,575 (254)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Computing all integer solutions of a genus 1 equation
The Elliptic Logarithm Method has been applied with great successto the problem of computing all integer solutions of equations ofdegree 3 and 4 defining elliptic curves. We extend this methodto include any equation f(u,v)=0 that defines a curve of genus
Stroeker, R.J., Tzanakis, N.
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
, 2007 Version définitive.International audienceWe establish new measures of linear independence of logarithms on commutative algebraic groups in the so-called \emph{rational case}.
Gaudron, Éric
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
On the exponential Diophantine equation (18m(2 )+1)(x) + (7m(2)-1)(y) = (5m)(z)
, 2018 Let m be a positive integer. We show that the exponential Diophantine equation (18m(2) + 1)(x) + (7m(2) - 1)(y) = (5m)(z) has only the positive integer solution (x, y, z) = (1, 1, 2) except for m 23, 47, 63, 87 (mod 120) . For m not equivalent to 0 (mod
ALAN, Murat
core +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
, 2006 This is the second in a series of papers where we combine the classical approach to exponential Diophantine equations (linear forms in logarithms, Thue equations, etc.) with a modular approach based on some of the ideas of the proof of Fermat's Last ...
Mignotte, Maurice +2 more
core +1 more source